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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 19.7
Human Site: S407 Identified Species: 36.11
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 S407 L S L Q S R C S I S K I S E H
Chimpanzee Pan troglodytes XP_524646 425 47381 S407 L S L Q S R C S V S K I S E H
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 E364 F K A K K N L E V R K N S G P
Dog Lupus familis XP_544446 502 56267 S484 L S L H S R C S V S K V P E H
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 S398 L S L Q S R C S V S K V S E H
Rat Rattus norvegicus P56718 416 46781 S398 L S L Q S R C S V S K V S E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 V395 S L Q S K F T V S K V S E H V
Chicken Gallus gallus Q9DDN6 385 43491 E368 F K A R K K L E A K K S Q F P
Frog Xenopus laevis P70031 453 51139 T428 P C R N F R D T D E D I A A T
Zebra Danio Brachydanio rerio NP_001073337 424 48183 S407 T D S R K S L S T Q V N N L D
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 A402 S R R V N H I A E Q D L I M E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437 F382 V N P L I Y N F M S G K R P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 R430 T A S R R A Q R P N P T G R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 93.3 13.3 73.3 N.A. 86.6 86.6 N.A. 0 6.6 13.3 6.6 0 N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 26.6 86.6 N.A. 100 100 N.A. 0 20 26.6 20 20 N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 0 0 8 0 8 8 0 0 0 8 8 0 % A
% Cys: 0 8 0 0 0 0 39 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 0 8 0 16 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 16 8 8 0 0 8 39 8 % E
% Phe: 16 0 0 0 8 8 0 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 0 8 39 % H
% Ile: 0 0 0 0 8 0 8 0 8 0 0 24 8 0 0 % I
% Lys: 0 16 0 8 31 8 0 0 0 16 54 8 0 0 0 % K
% Leu: 39 8 39 8 0 0 24 0 0 0 0 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 8 0 8 8 8 8 0 0 8 0 16 8 0 0 % N
% Pro: 8 0 8 0 0 0 0 0 8 0 8 0 8 8 16 % P
% Gln: 0 0 8 31 0 0 8 0 0 16 0 0 8 0 0 % Q
% Arg: 0 8 16 24 8 47 0 8 0 8 0 0 8 8 0 % R
% Ser: 16 39 16 8 39 8 0 47 8 47 0 16 39 0 0 % S
% Thr: 16 0 0 0 0 0 8 8 8 0 0 8 0 0 16 % T
% Val: 8 0 0 8 0 0 0 8 39 0 16 24 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _